Tenebrathin (1), a new C-5-substituted γ-pyrone with a nitroaryl side chain, was isolated from the rare actinomycete Streptoalloteichus tenebrarius NBRC 16177. The chemical structure of 1 was elucidated by a spectroscopic analysis using the crysta...
Yasuko Araki   Takayoshi Awakawa   Motomichi Matsuzaki   Rihe Cho   Yudai Matsuda   Shotaro Hoshino   Yasutomo Shinohara   Masaichi Yamamoto   Yasutoshi Kido   Daniel Ken Inaoka   Kisaburo Nagamune   Kotaro Ito   Ikuro Abe   Kiyoshi Kita   
Proceedings of the National Academy of Sciences of the United States of America 116(17) 8269-8274 2019年4月
Ascofuranone (AF) and ascochlorin (AC) are meroterpenoids produced by various filamentous fungi, including Acremonium egyptiacum (synonym: Acremonium sclerotigenum), and exhibit diverse physiological activities. In particular, AF is a promising dr...
Journal of industrial microbiology & biotechnology 46(3-4) 363-374 2019年3月
Bacterial secondary metabolites (SM) are rich sources of drug leads, and in particular, numerous metabolites have been isolated from actinomycetes. It was revealed by recent genome sequence projects that actinomycetes harbor much more secondary me...
Three new lignoids, premnan A (1), premnan B (2), and tauntangyiol C (3), were isolated from Premna serratifolia wood, a traditional cosmetic plant in Myanmar, together with a new lignoid, premnan C (4) assumed to be an artifact, one natural new l...
Phytochemical investigation of the CHCl3 extract of Premna serratifolia (syn: P. integrifolia) wood collected in Myanmar led to the isolation of a new tetrahydrofuran type lignan, 7,9-dihydroxydolichanthin B (1), together with two known...