M. Maekawa A. Watanabe Y. Iwayama T. Kimura K. Hamazaki S. Balan H. Ohba Y. Hisano Y. Nozaki T. Ohnishi M. Toyoshima C. Shimamoto K. Iwamoto M. Bundo N. Osumi E. Takahashi A. Takashima T. Yoshikawa
TRANSLATIONAL PSYCHIATRY 7(9) 1229 2017年9月 [査読有り]
The risk of schizophrenia is increased in offspring whose mothers experience malnutrition during pregnancy. Polyunsaturated fatty acids (PUFAs) are dietary components that are crucial for the structural and functional integrity of neural cells, an...
The E693 Delta (Osaka) mutation in APP is linked to familial Alzheimer's disease. While this mutation accelerates amyloid beta (A beta) oligomerization, only patient homozygotes suffer from dementia, implying that this mutation is recessive and ca...
Tau is a major component of the neurofibrillary tangles (NFT) that represent a pathological hallmark of Alzheimer's disease (AD). Although generally considered an axonal protein, Tau is found in the somato-dendritic compartment of degenerating neu...
Sleep-disordered breathing produces cognitive impairments, and is possibly associated with Alzheimer disease (AD). Intermittent hypoxia treatment (IHT), an experimental model for sleep-disordered breathing, results in cognitive impairments in anim...
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