Due to the growth in aging populations, prevention for cognitive decline and dementia are in great demand. We previously demonstrated that the consumption of iso-α-acids (IAA), the hop-derived bitter compounds in beer, prevents inflammation and Al...
Yuta Takaichi   Yasuhisa Ano   James K Chambers   Kazuyuki Uchida   Akihiko Takashima   Hiroyuki Nakayama   
Journal of Neuropathology & Experimental Neurology 77(10) 920-928 2018年10月 [査読有り]
Ano Y   Ayabe T   Kutsukake T   Ohya R   Takaichi Y   Uchida S   Yamada K   Uchida K   Takashima A   Nakayama H   
Frontiers in Neuroscience 12(12) 124 2018年3月 [査読有り]
Hippocampal hyperactivity, ascribed to amyloid ß (Aß)-induced imbalances in neural excitation and inhibition, is found in patients with mild cognitive impairment, a prodromal stage of Alzheimer's disease (AD). To better understand the relationship...
Yuta Takaichi   Yasuhisa Ano   James Ken Chambers   Kazuyuki Uchida   Akihiko Takashima   Hiroyuki Nakayama