高島明彦

研究者氏名	高島明彦
	タカシマアキヒコ
URL
所属	学習院大学
部署	理学部生命科学科
職名	教授
学位	理学博士
J-Global ID	200901009923564735

研究キーワード

老化 ,脳神経疾患 ,神経科学

研究分野

ライフサイエンス / 神経科学一般 /

学歴

1981年3月

九州大学大学院

1979年3月

九州大学理学部生物学科

論文

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Iso-α-Acids, the Bitter Components of Beer, Suppress Microglial Inflammation in rTg4510 Tauopathy

Yasuhisa Ano Yuta Takaichi Kazuyuki Uchida Keiji Kondo Hiroyuki Nakayama Akihiko Takashima

Molecules 23(12) 3133-3133 2018年11月 [査読有り]

Due to the growth in aging populations, prevention for cognitive decline and dementia are in great demand. We previously demonstrated that the consumption of iso-α-acids (IAA), the hop-derived bitter compounds in beer, prevents inflammation and Al...

Deposition of Phosphorylated α-Synuclein in the rTg4510 Mouse Model of Tauopathy

Yuta Takaichi Yasuhisa Ano James K Chambers Kazuyuki Uchida Akihiko Takashima Hiroyuki Nakayama

Journal of Neuropathology & Experimental Neurology 77(10) 920-928 2018年10月 [査読有り]

Frontotemporal dementia with Parkinsonism linked to chromosome-17 mutations enhance tau oligomer formation

Sumihiro Maeda Yuhei Sato Akihiko Takashima

Neurobiology of Aging 69 26-32 2018年9月 [査読有り]

Novel lactopeptides in fermented dairy products improve memory function and cognitive decline.

Ano Y Ayabe T Kutsukake T Ohya R Takaichi Y Uchida S Yamada K Uchida K Takashima A Nakayama H

Neurobiol Aging 6(72) 23-31 2018年8月 [査読有り]

Tau depletion in APP transgenic mice attenuates task-related hyperactivation of the hippocampus and differentially influences locomotor activity and spatial memory

Misato Yoshikawa Yoshiyuki Soeda Makoto Michikawa Osborne F.X. Almeida Akihiko Takashima

Frontiers in Neuroscience 12(12) 124 2018年3月 [査読有り]

Hippocampal hyperactivity, ascribed to amyloid ß (Aß)-induced imbalances in neural excitation and inhibition, is found in patients with mild cognitive impairment, a prodromal stage of Alzheimer's disease (AD). To better understand the relationship...