生命科学科 - 学習院大学研究者情報

研究キーワード

蛋白質 ,Protein

研究分野

ナノテク・材料 / 生体化学 /
ライフサイエンス / 分子生物学 /
ライフサイエンス / 構造生物化学 /

経歴

12 >

1991年

-

2007年

:学習院大学理学部助教授

1991年

-

2007年

:Associate Professor, Faculty of Science, Gakushuin University

2007年

-:学習院大学理学部教授

2007年

-:Professor, Faculty of Science, Gakushuin University

1989年

-

1991年

:東京大学工学部助手

学歴

12 >

-

1989年

東京大学工学系研究科工業化学専攻

-

1989年

東京大学

-

1986年

千葉大学理学研究科化学専攻

-

1986年

千葉大学

-

1984年

千葉大学理学部化学科

MISC

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Requirement of Ala residues at g position in heptad sequence of alpha-helix-forming peptide for formation of fibrous structure

Gaku Aoki Toyo K. Yamada Mayu Arii Shuichi Kojima Tadashi Mizoguchi

JOURNAL OF BIOCHEMISTRY 144(1) 15-19 2008年7月

One feature of the alpha 3-peptide, which has the amino acid sequence of (Leu-Glu-Thr-Leu-Ala-Lys-Ala)(3), that distinguishes it from many other alpha-helix-forming peptides is its ability to form fibrous assemblies that can be observed by transmi...

Effects of hydrophobic amino acid substitution in Pleurotus ostreatus proteinase A inhibitor 1 on its structure and functions as protease inhibitor and intramolecular chaperone

Shuichi Kojima Akane Iwahara Yuri Hisano Hideyuki Yanai

PROTEIN ENGINEERING DESIGN & SELECTION 20(5) 211-217 2007年5月

We previously demonstrated that Pleurotus ostreatus proteinase A inhibitor I (POIA1) could function as an intramolecular chaperone of subtilisin BPN', as in the case of the propeptide of subtilisin BPN', and that its Phe44 -> Ala mutant, which ...

Effects of hydrophobic amino acid substitution in Pleurotus ostreatus proteinase A inhibitor 1 on its structure and functions as protease inhibitor and intramolecular chaperone

Shuichi Kojima Akane Iwahara Yuri Hisano Hideyuki Yanai

PROTEIN ENGINEERING DESIGN & SELECTION 20(5) 211-217 2007年5月

We previously demonstrated that Pleurotus ostreatus proteinase A inhibitor I (POIA1) could function as an intramolecular chaperone of subtilisin BPN', as in the case of the propeptide of subtilisin BPN', and that its Phe44 -> Ala mutant, which ...

The effects of the side chains of hydrophobic aliphatic amino acid residues in an amphipathic polypeptide on the formation of α helix and its assocation

小島修一 Toshiaki Takei Atsuhito Okonogi Kumiko Tateno Akiko Kimura Shuichi Kojima Kazumori Yazaki. Kin-ichiro Miura

The Journal of Biochemistry 139(2) 271-278 2006年2月

The effects of the side chains of hydrophobic aliphatic amino acid residues in an amphipathic polypeptide on the formation of a helix and its association

T Takei A Okonogi K Tateno A Kimura S Kojima K Yazaki K Miura

JOURNAL OF BIOCHEMISTRY 139(2) 271-278 2006年2月

The polypeptide alpha 3, which was synthesized by us to produce an amphipathic helix structure, contains the regular three times repeated sequence (LETLAKA)(3), and alpha 3 forms a fibrous assembly. To clarify how the side chains of amino acid res...