The hydrosilylation of alkenes is one of the most important methods for the synthesis of organosilicon compounds. In addition to the platinum‐catalyzed hydrosilylation, silyl radical addition reactions are notable as economic reactions. ...
Tsubasa Sakamoto   Keiji Mori   Takahiko Akiyama   
ORGANIC LETTERS 14(13) 3312-3315 2012年7月
By use of 2-deuterated benzothiazoline as a deuterium donor in combination with a chiral phosphoric acid, the transfer deuteration of ketimine and alpha-iminoester took place smoothly to give alpha-deuterated amines in high yields with excellent e...
Keiji Mori   Taro Kawasaki   Takahiko Akiyama   
Organic Letters 14(6) 1436-1439 2012年3月
An expeditious route to furnish an isoquinoline skeleton via hydride shift mediated C-H bond functionalization was developed. In this process, an unusual [1,5]-H shift without the assistance of the adjacent heteroatom took place to produce tetrahy...
A benzothiazoline bearing 4-carboxyphenyl group at 2-position was developed as an efficient hydrogen donor for the transfer hydrogenation reaction. Introduction of the carboxyl group significantly facilitated the removal of the residual benzothiaz...
The chiral phosphoric acid-catalyzed enantioselective reductive amination of aliphatic ketones with aromatic amines was successfully achieved by the use of benzothiazoline as the hydrogen donor. Corresponding chiral aliphatic amines were obtained ...
Keiji Mori   Shosaku Sueoka   Takahiko Akiyama   
CHEMISTRY LETTERS 40(12) 1386-1388 2011年12月
The concise construction of 3-aryltetralin skeleton via hydride shift mediated C-H bond functionalization was achieved. In this process, the benzylic [1,5]-H shift occurred smoothly to furnish tetralin derivatives in good to excellent chemical yie...