The hydrosilylation of alkenes is one of the most important methods for the synthesis of organosilicon compounds. In addition to the platinum‐catalyzed hydrosilylation, silyl radical addition reactions are notable as economic reactions. ...
Asymmetric Synthesis II: More Methods and Applications 261-266 2013年1月
Chiral phosphoric acid derived from (R)-BINOL function efficiently as chiral Brønsted acid for a number of transformations
which include Mannich-type reactions, cycloaddition reactions, transfer hydrogenation reactions, Friedel-Crafts alkylation ...
Takahiko Akiyama Kohei Atobe Michiko Shibata Keiji Mori
Journal of Fluorine Chemistry 152 81-83 2013年
In the presence of 2 mol% of TiCl4, α,α,α- trifluorotoluene derivatives were reduced with LiAlH4 to furnish toluene derivatives in high yields. Selective reduction of bis(trifluoromethyl) benzene derivative is effected. The difference of the react...
A number of metal salt catalyzed enantioselective versions of Mannich and Mannich-type reactions were developed in the late 1990s. After emergence of organocatalysis in 2000, organocatalyzed versions of Mannich reactions have been extensively stud...
Masahiro Yamanaka Masaya Hoshino Takuya Katoh Keiji Mori Takahiko Akiyama
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (24) 4508-4514 2012年8月
A remarkable kinetic resolution was achieved in a chiral phosphoric acid catalyzed intramolecular aldol reaction. Its combination with an enantioselective Michael reaction resulted in the formation of cyclohexenone derivatives with excellent enant...
人文科学研究科
理学部