Shotaro Hoshino

(星野翔太郎)

Profile Information

Affiliation: Assistant professor, Faculty of Science Department of Life Science, Gakushuin University

Degree: Ph.D. (Pharmaceutical Science)(Mar, 2019, The University of Tokyo)

Researcher number: 10962988
ORCID ID: https://orcid.org/0000-0002-7502-5072
J-GLOBAL ID: 202201002402026891
researchmap Member ID: R000034538

Research Interests

Research Areas

Research History

Apr, 2023 - Present

Assistant professor, Faculty of Science Department of Life Science, Gakushuin University
Apr, 2022 - Mar, 2023

Project Assistant Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Dec, 2021 - Feb, 2022

Postdoctoral Researcher, Princeton University Department of Chemistry
Jun, 2019 - Nov, 2021

Postdoctoral Researcher, Princeton University Department of Chemistry, JSPS Postdoctral Fellowship for Research Abroad
Apr, 2019 - May, 2019

Reserch Fellow, Graduate School of Pharmaceutical Sciences, The University of Tokyo

Education

Apr, 2016 - Mar, 2019

Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Apr, 2014 - Mar, 2016

Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Apr, 2012 - Mar, 2014

Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, The University of Tokyo
Apr, 2010 - Mar, 2012

Natural Science I, College of Arts and Sciences, The University of Tokyo

Committee Memberships

Aug, 2024 - Present

世話人, 天然物化学談話会

Awards

Jul, 2024

学術奨励賞, 放線菌未利用二次代謝経路を活用した新規天然物の探索研究, 日本生薬学会

星野翔太郎
Jun, 2023

Incentive Research in 2023, Exploiting untapped secondary metabolic pathways in actinomycetes to discover novel natural products, The Pharmaceutical Society of Japan Division of Natural Medicines

Shotaro Hoshino
Mar, 2023

Hot Topics Award at Annual Meeting of JSBBA 2023, Studies on arsenic-related secondary metabolism in actinobacteria, Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA)

Shotaro Hoshino, Shumpei Asamizu, Hiroyasu Onaka
Sep, 2022

2022 Poster Presentation Award, Studies on organo-arsenic secondary metabolites produced by actinobacteria, The Society for Actinomycetes Japan

Shotaro Hoshino, Shumpei Asamizu, Hiroyasu Onaka
Apr, 2018

日本薬学会第138年会優秀発表賞, 『複合培養法を利用した希少放線菌からの生物活性物質探索』, 日本薬学会

星野翔太郎, 淡川孝義, 浅水俊平, 尾仲宏康, 阿部郁朗

Papers

Two new neo-clerodane diterpenoids from Tinospora cordifolia stems

Nhat Nam Hoang, Shotaro Hoshino, Takeshi Kodama, Thao Xuan Hoang, Hiroyasu Onaka, Hiroyuki Morita

Phytochemistry Letters, 63 54-59, Oct, 2024
Five pimarane diterpenoids from Kaempferia champasakensis and their cytotoxic activities

Kiep Minh Do, Shotaro Hoshino, Takeshi Kodama, Hien Minh Nguyen, Naotaka Ikumi, Hiroyasu Onaka, Hiroyuki Morita

Journal of Natural Medicines, Jul 2, 2024
Three neo-Clerodane Diterpenoids from Tinospora cordifolia Stems and Their Arginase Inhibitory Activities

Nhat Nam Hoang, Shotaro Hoshino, Takeshi Kodama, Yu Nakashima, Kiep Minh Do, Hoang Xuan Thao, Naotaka Ikumi, Hiroyasu Onaka, Hiroyuki Morita

Chemical and Pharmaceutical Bulletin, 72(6) 540-546, Jun 12, 2024 Peer-reviewed
A new 3,4-seco-isopimarane and three new isopimarane diterpenoids from Kaempferia champasakensis collected from Vietnam and their cytotoxic activities

Kiep Minh Do, Shotaro Hoshino, Takeshi Kodama, Hien Minh Nguyen, Son Van Le, Naotaka Ikumi, Hiroyasu Onaka, Hiroyuki Morita

Journal of Natural Medicines, Mar 22, 2024
Recent advances in the biosynthetic studies of bacterial organoarsenic natural products

Shotaro Hoshino, Hiroyasu Onaka, Ikuro Abe

Natural Product Reports, 2024

Misc.

No Title

Shotaro Hoshino, Hiroyasu Onaka

BIOSCIENCE & INDUSTRY, 82(3) 296-298, May, 2024 InvitedLead author
Analysis of oxidoreductase responsible for the formation of a new solabionin scaffold

伊地知新太, 星野翔太郎, 浅水俊平, 浅水俊平, 尾仲宏康, 尾仲宏康

日本農芸化学会大会講演要旨集(Web), 2023, 2023
Studies on arsenic-related secondary metabolism in actinobacteria

星野翔太郎, 浅水俊平, 浅水俊平, 尾仲宏康, 尾仲宏康

日本農芸化学会大会講演要旨集(Web), 2023, 2023
Exploration of arsenic secondary metabolic pathways distributed in actinomycetes

星野翔太郎, 浅水俊平, 尾仲宏康

日本放線菌学会大会講演要旨集, 37th, 2023
Sulfoxidation of labionin enhances antibacterial activity

伊地知新太, 星野翔太郎, 浅水俊平, 尾仲宏康

日本放線菌学会大会講演要旨集, 37th, 2023
「Overseas research in United States under covid-19 crisis）

Shotaro Hoshino

Kagaku to Seibutsu, 60(4) 205-209, Apr, 2022 Peer-reviewedInvitedLead author
Isotope-guided metabolomics reveals polar-functionalized fatty-acylated ribosomally synthesized and posttranslationally modified peptides

浅水俊平, 星野翔太郎, 伊地知新太, JO Hanseam, 尾仲宏康

日本放線菌学会大会講演要旨集, 36th, 2022
Studies on organo-arsenic secondary metabolites produced by actinobacteria

星野翔太郎, 浅水俊平, 浅水俊平, 尾仲宏康, 尾仲宏康

日本放線菌学会大会講演要旨集, 36th, 2022
Study of thiopeptides heterologous production platform focused on transcriptional terminators

伊地知新太, 永井栄美子, 星野翔太郎, 浅水俊平, 浅水俊平, 尾仲宏康, 尾仲宏康

日本放線菌学会大会講演要旨集, 36th, 2022
シトクロムP450酸化酵素TleBを用いた硫黄を含む新奇indolactam類縁体化合物の創出

森田伊織, 星野翔太郎, 三橋隆章, 森貴裕, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 139th, 2019
希少放線菌Streptoalloteichus tenebrarius NBRC16177株が産生する二次代謝産物に関する研究

星野翔太郎, 淡川孝義, 三橋隆章, WONG Chin Piow, 森田洋行, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 139th, 2019
糸状菌由来新規異性化酵素のX線結晶構造解析

森貴裕, 岩渕大輝, 星野翔太郎, 松田侑大, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 138th, 2018
複合培養法を利用した大環状ポリエンマクロラクタム分子の環化誘導

尾関雅弘, 星野翔太郎, 尾仲宏康, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 138th, 2018
複合培養法を利用した希少放線菌からの生物活性物質探索

星野翔太郎, 淡川孝義, 浅水俊平, 尾仲宏康, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 138th, 2018
希少放線菌に対する複合培養法の適用と新規二次代謝産物の獲得

星野翔太郎, 淡川孝義, 尾仲宏康, 阿部郁朗

日本放線菌学会大会講演要旨集, 33rd, 2018
複合培養を利用した希少放線菌における潜在的二次代謝能の覚醒

星野翔太郎, 淡川孝義, 尾仲宏康, 阿部郁朗

日本放線菌学会大会講演要旨集, 32nd, 2017
複合培養法を用いた希少放線菌からの医薬品資源探索

星野翔太郎, 淡川孝義, 岡田正弘, 浅水俊平, 尾仲宏康, 阿部郁朗

食品薬学シンポジウム講演要旨集, 7th, 2017
複合培養法を用いた希少放線菌からの新規生物活性物質探索

星野翔太郎, 張恵平, 林文晶, 尾仲宏康, 阿部郁朗

日本生薬学会年会講演要旨集, 64th, 2017
放線菌における翻訳後修飾を担うisoprenyl tryptophan synthaseの探索及び機能解明

星野翔太郎, 岡田正弘, 淡川孝義, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 137th, 2017
糸状菌Emericella variecolorに由来する新規セスタテルペノイドの探索

三橋隆章, 岡田正弘, 松田侑大, 星野翔太郎, 森貴裕, 中川和也, QUAN Zhi Yang, QIN Bin, 川出洋, 阿部郁朗

天然薬物の開発と応用シンポジウム講演要旨集, 21st, 2016
Sphaerobacter thermophilusにおけるComXフェロモン生成機構の解明

杉田智惇, 秋田航平, 田添, 星野翔太郎, 森貴裕, 松田侑大, 淡川孝義, 岡田正弘, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 136th, 2016
複合培養法を用いた新規macrolactam類の単離構造決定

星野翔太郎, 岡田正弘, 張恵平, 林文晶, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 136th, 2016
放線菌における翻訳後修飾を担うトリプトファンイソプレニル化酵素の探索及び機能解明研究

星野翔太郎, 岡田正弘, 淡川孝義, 阿部郁朗

天然薬物の開発と応用シンポジウム講演要旨集, 21st, 2016
複合培養を用いたStreptomyces属放線菌由来新規二次代謝産物の探索

星野翔太郎, 張驪駻, 淡川孝義, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本薬学会年会要旨集(CD-ROM), 135th, 2015
複合培養法によるStreptomyces属放線菌由来新規二次代謝産物の探索

星野翔太郎, ZHANG Lihan, 淡川孝義, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本放線菌学会大会講演要旨集, 30th, 2015
複合培養法によりStreptomyces属放線菌から単離された新規macrolactam類の構造決定

星野翔太郎, 張恵平, 林文晶, 岡田正弘, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本生薬学会年会講演要旨集, 62nd, 2015
複合培養法を利用したStreptomyces属放線菌からの新規薬用資源探索

星野翔太郎, 岡田正弘, ZHANG Huiping, 林文晶, 脇本敏幸, 尾仲宏康, 阿部郁朗

食品薬学シンポジウム講演要旨集, 6th, 2015
ミコール酸含有微生物Tsukamurella pulmonisとの複合培養による,放線菌Streptomyces属由来新規生物活性物質の探索

星野翔太郎, LIHAN Z., 淡川孝義, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本放線菌学会大会講演要旨集, 29th, 2014
ミコール酸含有微生物との複合培養による,Streptomyces属放線菌由来新規生物活性物質の探索

星野翔太郎, ZHANG Lihan, 淡川孝義, 脇本敏幸, 尾仲宏康, 阿部郁朗

天然薬物の開発と応用シンポジウム講演要旨集, 20th, 2014
ミコール酸含有微生物との複合培養を用いた,放線菌Streptomyces属由来新規生物活性物質の探索

星野翔太郎, 張驪駻, 淡川孝義, 脇本敏幸, 尾仲宏康, 阿部郁朗

日本生薬学会年会講演要旨集, 61st, 2014
異種発現系を用いた新規Teleocidin類の生産

星野翔太郎, ZHANG Lihan, 淡川孝義, 伊藤卓也, 脇本敏幸, 阿部郁朗

日本農芸化学会大会講演要旨集(Web), 2014, 2014

Presentations

Organoarsenic-related secondary metabolic pathway found in actinomycetes

Shotaro Hoshino

1st Japan-Korea Actinomycetes Symposium, Jun 17, 2024
Actinomycetes expand the field of organoarsenic natural products

Shotaro Hoshino

The 144th Annual Meeting of the Pharmaceutical Society of Japan (Yokohama), Mar 29, 2024 Invited
Accumulation of unexplored natural product biosynthetic pathway based on novel C-As bond forming reaction

Shotaro Hoshino

Feb 16, 2024
Actinomycetes expand the diversity of organoarsenic natural products

Shotaro Hoshino, Shinta Ijichi, Shumpei Asamizu, Hiroyasu Onaka

2023 The 1st Taiwan-Japan Bilateral Symposium on Natural Products Biosynthesis, Dec 25, 2023 Invited
Studies on arsenic-related secondary metabolism in actinobacteria

Shotaro Hoshino

Nov 10, 2023 Invited

Teaching Experience

Apr, 2023 - Present

- (Gakushuin University)
Apr, 2023 - Present

- (Gakushuin University)
Apr, 2023 - Present

- (Gakushuin University)
Apr, 2023 - Present

- (Gakushuin University)
Apr, 2023 - Present

- (Gakushuin University)

Professional Memberships

Nov, 2014 - Present

The Pharmaceutical Society of Japan
Jun, 2014 - Present

The Japanese Society of Pharmacognosy
Apr, 2014 - Present

Society for Actinomycetes Japan
Mar, 2014 - Present

Japan Society for Bioscience, Biotechnology, and Agrochemistry

Research Projects

新規炭素-ヒ素結合形成反応を基盤とした未開拓天然物生合成経路の集積

科学研究費助成事業, 日本学術振興会, Apr, 2023 - Mar, 2025

星野翔太郎
放線菌におけるヒ素二次代謝経路の開拓及び新規ヒ素二次代謝産物の探索研究

科学研究費助成事業研究活動スタート支援, 日本学術振興会, Aug, 2022 - Mar, 2024

星野翔太郎
Activation of cryptic biosynthetic gene clusters in actinomycetes using high-thr oughput elicitor screening

Overseas Reserch Fellowships, Japan Society for the Promotinon of Science, Jun, 2019 - Nov, 2021

Shotaro Hoshino
Investigation for ComX pheromone-like molecules in Streptomyces bacteria

Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

To the list screen