Curriculum Vitaes

Issei Mabuchi

(馬渕一誠)

Profile Information

Affiliation: Faculty of Science, Department of Life Science, Gakushuin University

Degree: D.Sci.(The University of Tokyo)

J-GLOBAL ID: 200901003222420021
researchmap Member ID: 1000011783

External link: http://bio.c.u-tokyo.ac.jp/labs/mabuchi/

Research Interests

8

Research Areas

3

Research History

15

1997 - 2002

岡崎国立共同研究機構基礎生物学研究所教授（併任）
1997 - 2002

Adjunctive Professor, National Institute for Basic Biology
1990 - 1996

College of Arts and Sciences, The University of Tokyo
1990 - 1996

Professor, College of Arts and Science, University of Tokyo
1996

- 東京大学大学院総合文化研究科教授

Education

4

Committee Memberships

1

1988 - 1991

運営委員, 日本細胞生物学会

Awards

2

1992

井上学術賞
1990

日本動物学会賞

Misc.

67

Myosin-II reorganization during mitosis is controlled temporally by its dephosphorylation and spatially by Mid1 in fission yeast

F Motegi, M Mishra, MK Balasubramanian, Mabuchi, I

JOURNAL OF CELL BIOLOGY, 165(5) 685-695, Jun, 2004
A novel actin-bundling kinesin-related protein from Dictyostelium discoideum

S Iwai, A Ishiji, Mabuchi, I, K Sutoh

JOURNAL OF BIOLOGICAL CHEMISTRY, 279(6) 4696-4704, Feb, 2004
An IQGAP-like protein is involved in actin assembly together with Cdc42 in the sea urchin egg

Y Nishimura, Mabuchi, I

CELL MOTILITY AND THE CYTOSKELETON, 56(4) 207-218, Dec, 2003
Localization of two IQGAPs in cultured cells and early embryos of Xenopus laevis

S Yamashiro, T Noguchi, Mabuchi, I

CELL MOTILITY AND THE CYTOSKELETON, 55(1) 36-50, May, 2003
The small GTPase Rho4 is involved in controlling cell morphology and septation in fission yeast

K Nakano, T Mutoh, R Arai, Mabuchi, I

GENES TO CELLS, 8(4) 357-370, Apr, 2003
細胞が分裂する時、収縮環はどのようにして形成されるか。

学術月報, 56, 1243-1252, 2003
The small GTPase Rho3 and the diaphanous/formin For3 function in polarized cell growth in fission yeast

K Nakano, J Imai, R Arai, A Toh-e, Y Matsui, Mabuchi, I

JOURNAL OF CELL SCIENCE, 115(23) 4629-4639, Dec, 2002
Microtuble organization in Xenopus eggs during the first cleavage and its role in cytokinesis

M Takayama, T Noguchi, S Yamashiro, Mabuchi, I

CELL STRUCTURE AND FUNCTION, 27(4) 163-171, Aug, 2002
細胞分裂における収縮環形成の過程

生体の科学, 53, 173-185, 2002
Importance of a myosin Ⅱ-containing progenitor for actomyosin ring assembly in fission yeast.

Curr. Biol., 12 1-20, 2002
Localized calcium signals along the cleavage furrow of the Xenupus egg are not involved in cytokinesis.

Mol. Biol. Cell., 13 1263-1273, 2002
F-actin ring formation and roles of F-actin cables in the fission yeast Schizosaccharomyces pombe.

J.Cell Sci., 115 887-898, 2002
Spinning actin to divide.

Nature, 419, 27-28, 2002
Importance of a myosin Ⅱ-containing progenitor for actomyosin ring assembly in fission yeast.

Curr. Biol., 12 1-20, 2002
Localized calcium signals along the cleavage furrow of the Xenupus egg are not involved in cytokinesis.

Mol. Biol. Cell., 13 1263-1273, 2002
F-actin ring formation and roles of F-actin cables in the fission yeast Schizosaccharomyces pombe.

J.Cell Sci., 115 887-898, 2002
Characterization of GTPase-activating proteins for the function of the Rho-family small GTPases in the fission yeast Schizosaccharomyces pombe

K Nakano, T Mutoh, Mabuchi, I

GENES TO CELLS, 6(12) 1031-1042, Dec, 2001
Interactions among a fimbrin, a capping protein, and an actin-depolymerizing factor in organization of the fission yeast actin cytoskeleton

K Nakano, K Satoh, A Morimatsu, M Ohnuma, Mabuchi, I

MOLECULAR BIOLOGY OF THE CELL, 12(11) 3515-3526, Nov, 2001
The gelsolin/fragmin family protein identified in the higher plant Mimosa pudica

S Yamashiro, K Kameyama, N Kanzawa, T Tamiya, Mabuchi, I, T Tsuchiya

JOURNAL OF BIOCHEMISTRY, 130(2) 243-249, Aug, 2001
Identification of two type V myosins in fission yeast, one of which functions in polarized cell growth and moves rapidly in the cell

F Motegi, R Arai, Mabuchi, I

MOLECULAR BIOLOGY OF THE CELL, 12(5) 1367-1380, May, 2001
Calyculin-A, an inhibitor for protein phosphatases, induces cortical contraction in unfertilized sea urchin eggs

Y Asano, Mabuchi, I

CELL MOTILITY AND THE CYTOSKELETON, 48(4) 245-261, Apr, 2001
Identification and functional analysis of the gene for type I myosin in fission yeast

M Toya, F Motegi, K Nakano, Mabuchi, I, M Yamamoto

GENES TO CELLS, 6(3) 187-199, Mar, 2001
Heterogeneity of mRNAs coding for Caenorhabditis elegans coronin-like proteins.

YONEMURA I, MABUCHI I

Gene., 271(2) 255-259, 2001
Contractile ring formation in Xenopus egg and fission yeast

Tatsuhiko Noguchi, Ritsuko Arai, Fumio Motegi, Kentaro Nakano, Issei Mabuchi

Cell Structure and Function, 26(6) 545-554, 2001
Heterogeneity of mRNAs coding for Caenorhabditis elegans coronin-like proteins.

Gene., 271(2) 255-259, 2001
Reorganization of actin cytoskeleton at the growing end of the cleavage furrow of Xenopus egg during cytokinesis

T Noguchi, Mabuchi, I

JOURNAL OF CELL SCIENCE, 114(2) 401-412, Jan, 2001
The S-pombe rlc1 gene encodes a putative myosin regulatory light chain that binds the type II myosins myo3p and myo2p

Le Goff, X, F Motegi, E Salimova, Mabuchi, I, Simanis, V

JOURNAL OF CELL SCIENCE, 113(23) 4157-4163, Dec, 2000
Molecular mechanism of myosin-II assembly at the division site in Schizosaccharomyces pombe

F Motegi, K Nakano, Mabuchi, I

JOURNAL OF CELL SCIENCE, 113(10) 1813-1825, May, 2000
Schizosaccharomyces pombe Rho2 GTPase regulates cell wall a-glucan biosynthesis, through the protein kinase Pck2.

Mol. Biol. Cell., 11 4393-4401, 2000
Schizosaccharomyces pombe Rho2 GTPase regulates cell wall a-glucan biosynthesis, through the protein kinase Pck2.

Mol. Biol. Cell., 11 4393-4401, 2000
Rho-dependence of Schizosaccharomyces pombe Pck2

LG Sayers, S Katayama, K Nakano, H Mellor, Mabuchi, I, T Toda, PJ Parker

GENES TO CELLS, 5(1) 17-27, Jan, 2000
Overproduction of elongation factor 1 alpha, an essential translational component, causes aberrant cell morphology by affecting the control of growth polarity in fission yeast

M Suda, M Fukui, Y Sogabe, K Sato, A Morimatsu, R Arai, F Motegi, T Miyakawa, Mabuchi, I, D Hirata

GENES TO CELLS, 4(9) 517-527, Sep, 1999
Localization of Rho GTPase in sea urchin eggs

Y Nishimura, K Nakano, Mabuchi, I

FEBS LETTERS, 441(1) 121-126, Dec, 1998
Subcellular localization of actin, tropomyosin and actin-related protein 3(Arp3)in Schizosaccharomyces pombe.

Eur. J. Cell Biol. ,, 76 288-295, 1998
Genes that cause aberrant cell morphology by overexpression in fission yeast: a role of a small GTP-binding protein Rho2 in cell morphogenesis

D Hirata, K Nakano, M Fukui, H Takenaka, T Miyakawa, Mabuchi, I

JOURNAL OF CELL SCIENCE, 111 149-159, Jan, 1998
Identification of Myo3, a second type-II myosin heavy chain in the fission yeast Schizosaccharomyces pombe

Fumio Motegi, Kentaro Nakano, Chikako Kitayama, Masayuki Yamamoto, Issei Mabuchi

FEBS Letters, 420(2-3) 161-166, Dec 29, 1997
Purealin blocks the sliding movement of sea urchin flagellar axonemes by selective inhibition of half the ATpase activity of axonemal dyneins

Yang-Il Fang, Etsuo Yokota, Issei Mabuchi, Hideshi Nakamura, Yasushi Ohizumi

Biochemistry, 36(50) 15561-15567, Dec 16, 1997
Isolation of cleavage furrows from eggs of regular sea urchins and identification of furrow-specific proteins

H Fujimoto, Mabuchi, I

JOURNAL OF BIOCHEMISTRY, 122(3) 518-524, Sep, 1997
The small GTP-binding protein, Rho1, is a multi-functional protein that is involved in the regulation of actin localozation, cell polarity, and septum formation in the fission yeast, Schizosaccharomyces pombe.

Genes to Cells, 2(11) 679-694, 1997
Involvement of p34cdc2 kinase from sea urchin Hemicentrotus pulcherrimus in the phosphorylation of myosin II regulatory light chain in the metaphase extract.

Gene,, 198(1/2) 359-365, 1997
Identification of novel F-actin binding proteins by F-actin affinity column chromatography from sea urchin eggs.

J. Biochem., 122 226-236, 1997
A single Drosophila melanogaster myosin light chain kinase gene produces multiple isoforms whose activities are differently regulated

SI Kojima, M Mishima, Mabuchi, I, Y Hotta

GENES TO CELLS, 1(9) 855-871, Sep, 1996
Interaction of flagellar inner arm dynein isolated from sea urchin sperm with microtubules in the presence of ATP.

Eur. J. Cell Biol., 72 214-221, 1996
Cell Cycle-dependent phosphorylation of smooth muscle myosin light chain in sea urchin egg extracts.

J. Biochemistry, 119,906-913, 1996
Rhoと細胞質分裂

実験医学, 14,297-300, 1995
Isolation and sequencing of two cDNA clones encoding Rho proteins from the fission yeast ┣DBSchizosaccharomyces pombe(/)-┫DB. (共著)

Gene, 155,119-121, 1995
C/A dynein isolated from sea urchin Sperm flagellar axonemes : enzymatic properties and interaction with microtubules. (共著)

Journal of Cell Science, 107,353-361, 1994
Isolation and characterization of a novel dynein that contains C and A heavy chains from sea urchin sperm flagellar axonemes. (共著)

Journal of Cell Science, 107,345-351, 1994
Cleavage furrow : timing of emergence of contractile ring actin filaments and establishment of the contractile ring by filament bundling in sea urchin eggs.

Journal of Cell Science, 107,1853-1862, 1994
現代医学、生物学の仮説、学説:細胞質分裂。

生体の科学, 44,426-429, 1993

Books and Other Publications

8

タンパク質がわかる

羊土社（執筆分担）, 2003
細胞の誕生と死

共立出版（執筆分担）, 2001
細胞骨格と筋肉のタンパク質

広川タンパク質化学第6巻, 1997
細胞生物学の基礎技術

羊土社, 1997
現代の細胞生物学

講談社, 1996

Professional Memberships

6

Works

2

細胞質分裂シグナル伝達と収縮環形成のメカニズム

1998 - 2001
Mechanisms of cleavage signaling and contractile ring formation

1998 - 2001

Research Projects

6

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