Neurochemistry international 139 104808-104808 2020年10月 [査読有り]
The molecular mechanism responsible for hyperphosphorylated tau accumulation in dendrites of Alzheimer's disease (AD) neurons has not been fully clarified. Recently, we reported that tau mRNA is distributed into dendrites, and that translation and...
Neurodegenerative diseases are characterized by the accumulation of specific phosphorylated protein aggregates in the brain, such as hyperphosphorylated tau (hp-tau) in tauopathies and phosphorylated α-synuclein (p-αSyn) in α-synucleinopathies. Th...
Frontiers in molecular neuroscience 13 590896-590896 2020年 [査読有り]
Microtubule-associated protein tau is characterized by the fact that it is an intrinsically disordered protein due to its lack of a stable conformation and high flexibility. Intracellular inclusions of fibrillar forms of tau with a β-sheet structu...
Yasuhisa Ano Rena Ohya Yuta Takaichi Terukatsu Washinuma Kazuyuki Uchida Akihiko Takashima Hiroyuki Nakayama
Journal of Alzheimer's disease : JAD 73(4) 1331-1342 2020年 [査読有り]
The prevention of age-related memory decline and dementia has been becoming a high priority because of the rapid growth in aging populations. Accumulating epidemiological and clinical studies indicate that intake of fermented dairy products rich i...
人文科学研究科
理学部