Molecular and cellular biology 41(4) 2021年3月 [査読有り]
In eukaryotes, genomic DNA is packaged into nucleosomes, which are the basal components coordinating both the structures and functions of chromatin. In this study, we screened a collection of mutations for histone H3/H4 mutants in Saccharomyces ce...
Nutrients including glucose, nitrogen, sulfur, zinc, and iron are involved in the regulation of chronological lifespan (CLS) of yeast, which serves as a model of the lifespan of differentiated cells of higher organisms. Herein, we show that magnes...
Hiraku Takada Mohammad Roghanian Julien Caballero-Montes Katleen Van Nerom Steffi Jimmy Pavel Kudrin Fabio Trebini Rikinori Murayama Genki Akanuma Abel Garcia-Pino Vasili Hauryliuk
Nucleic acids research 49(1) 444-457 2021年1月 [査読有り]
In the Gram-positive Firmicute bacterium Bacillus subtilis, amino acid starvation induces synthesis of the alarmone (p)ppGpp by the RelA/SpoT Homolog factor Rel. This bifunctional enzyme is capable of both synthesizing and hydrolysing (p)ppGpp. To...
Hiraku Takada Mohammad Roghanian Victoriia Murina Ievgen Dzhygyr Rikinori Murayama Genki Akanuma Gemma C Atkinson Abel Garcia-Pino Vasili Hauryliuk
Frontiers in microbiology 11 277-277 2020年2月 [査読有り]
The (p)ppGpp-mediated stringent response is a bacterial stress response implicated in virulence and antibiotic tolerance. Both synthesis and degradation of the (p)ppGpp alarmone nucleotide are mediated by RelA-SpoT Homolog (RSH) enzymes which can ...
Huyen Thi Minh Nguyen Genki Akanuma Tu Thi Minh Hoa Yuji Nakai Keitarou Kimura Kazutaka Yamamoto Takashi Inaoka
Applied and environmental microbiology 86(1) 2019年12月 [査読有り]
Vegetative cells of Bacillus subtilis can recover from injury after high-hydrostatic-pressure (HHP) treatment at 250 MPa. DNA microarray analysis revealed that substantial numbers of ribosomal genes and translation-related genes (e.g., translation...
人文科学研究科
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