生命科学科 - 学習院大学研究者情報

研究キーワード

蛋白質 ,Protein

研究分野

ナノテク・材料 / 生体化学 /
ライフサイエンス / 分子生物学 /
ライフサイエンス / 構造生物化学 /

経歴

12 >

1991年

-

2007年

:学習院大学理学部助教授

1991年

-

2007年

:Associate Professor, Faculty of Science, Gakushuin University

2007年

-:学習院大学理学部教授

2007年

-:Professor, Faculty of Science, Gakushuin University

1989年

-

1991年

:東京大学工学部助手

学歴

12 >

-

1989年

東京大学工学系研究科工業化学専攻

-

1989年

東京大学

-

1986年

千葉大学理学研究科化学専攻

-

1986年

千葉大学

-

1984年

千葉大学理学部化学科

MISC

<3 456 7 >

Stabilization of the fibrous structure of an alpha-helix-forming peptide by sequence reversal

S Kojima Y Kuriki K Yazaki K Miura

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 331(2) 577-582 2005年6月

The α 3-peptide, which comprises three repeats of the sequence Leu-Glu-Thr-Leu-Ala-Lys-Ala and forms an amphipathic of-helix, is unique among various α-helix-forming peptides in that it assembles into fibrous structures that can be obs...

Mapping the position of the transition stare in the folding of a small α/β protein, POIA1

小島修一 Shuhei Tanaka Shuichi Kojima Atsuo Tamura

Chemical Physics 307(2-3) 233-242 2004年12月

Mapping the position of the transition state in the folding of a small alpha/beta protein, POIA1

S Tanaka S Kojima A Tamura

CHEMICAL PHYSICS 307(2-3) 233-242 2004年12月

The kinetics of the folding of a small protein, POIA1, and its two variants lacking proline residues, has been investigated by using stopped-flow measurements. Although all these proteins fold and unfold in a two-state manner, logarithms of the ob...

Low pH facilitates uptake of proteins by cells through a non-endocytic pathway

M Motizuki T Takei K Tasaka S Yokota S Kojima T Haga K Tsurugi

JOURNAL OF BIOCHEMISTRY 135(6) 713-719 2004年6月

We previously noted that bovine apolipoprotein A-II (apoA-II) had a bactericidal effect causing morphological changes in the cytoplasm. To determine whether and how apoA-II and apoA-I, which have acidic isoelectric points (pIs), enter cells, we de...

Low pH facilitates uptake of proteins by cells through a non-endocytic pathway

M Motizuki T Takei K Tasaka S Yokota S Kojima T Haga K Tsurugi

JOURNAL OF BIOCHEMISTRY 135(6) 713-719 2004年6月

We previously noted that bovine apolipoprotein A-II (apoA-II) had a bactericidal effect causing morphological changes in the cytoplasm. To determine whether and how apoA-II and apoA-I, which have acidic isoelectric points (pIs), enter cells, we de...