Xuan Shi   Takuya Miyakawa   Akira Nakamura   Feng Hou   Makoto Hibi   Jun Ogawa   Yeondae Kwon   Masaru Tanokura   
SCIENTIFIC REPORTS 7 13703 2017年10月 [査読有り]
Fenugreek is a dietary supplement for anti-aging and human health. (2S, 3R, 4S)-4-hydroxyisoleucine (4-HIL), which is extracted from fenugreek seeds, is expected to be a promising orally active drug for diabetes and diabetic nephropathy because of...
Laminarinase from Flavobacterium sp. strain UMI-01, a new member of the glycosyl hydrolase 16 family of a marine bacterium associated with seaweeds, mainly degrades beta-1,3-glucosyl linkages of beta-glucan (such as laminarin) through the hydrolys...
Mitochondrial isocitrate dehydrogenase 2 (IDH2) converts NADP(+) to NADPH and promotes regeneration of reduced glutathione (GSH) by supplying NADPH to glutathione reductase or thioredoxin reductase. We have previously shown that under calorie rest...
JOURNAL OF BIOLOGICAL CHEMISTRY 292(6) 2182-2190 2017年2月 [査読有り]
Alginate is an abundant algal polysaccharide, composed of beta-D-mannuronate and its C5 epimer alpha-L-guluronate, that is a useful biomaterial in cell biology and tissue engineering, with applications in cancer and aging research. The alginate ly...
<p>Microgravity environment has been used to obtain high-quality crystals. Strong magnetic force produced by a superconducting magnet can cancel out the gravity force, enabling construction of quasi-microgravity environment on earth. We developed ...