The hydrosilylation of alkenes is one of the most important methods for the synthesis of organosilicon compounds. In addition to the platinum‐catalyzed hydrosilylation, silyl radical addition reactions are notable as economic reactions. ...
Kosaku Horiguchi Eri Yamamoto Kodai Saito Masahiro Yamanaka Takahiko Akiyama
CHEMISTRY-A EUROPEAN JOURNAL 22(24) 8078-8083 2016年6月
Asymmetric synthesis of tetrahydrobenzodiazepines was achieved by transfer hydrogenation of dihydrobenzodiazepines with benzothiazoline having a hydrogenbonding donor substituent by means of a newly synthesized chiral phosphoric acid. This method ...
Takahiko Akiyama was born in Kurashiki (Japan) in 1958 and did his undergraduate and graduate studies at The University of Tokyo. After working at Shionogi Research Laboratories, Shionogi & Co., Ltd., as a research chemist, he was appointed as an ...
A strategy for oxidative kinetic resolution of racemic indolines was developed, employing salicylaldehyde derivative as the pre-resolving reagent and chiral phosphoric acid as the catalyst. The iminium intermediate, formed by the condensation reac...
The titanium tetrachloride-catalyzed hydrodefluorination reaction of trifluorotoluene derivatives was developed using triethylsilane as the reducing agent. The reaction produced various toluene derivatives with high chemoselectivities by means of ...
Described herein are differences in behavior between a Hantzsch ester and a benzothiazoline as hydrogen donors in the chiral phosphoric acid catalyzed asymmetric reductive amination of ketones with p-anisidine. The asymmetric reductive amination o...
人文科学研究科
理学部